Semax
A nootropic peptide studied for cognitive enhancement and focus.
Overview
Semax is a synthetic analogue of the adrenocorticotropic hormone (ACTH) fragment 4-10, designed to resist enzymatic breakdown. It is one of the most well-known nootropic peptides, researched for improvements in memory, attention, learning, and neuroprotection.
Dosing
Nasal
- Starting dose
- 200 mcg
- Common dose
- 400–800 mcg
- Frequency
- 1–2× daily
- Notes
- 0.1% solution ≈ 50 mcg/drop; run in short cycles.
Injection
- Starting dose
- 100 mcg
- Common dose
- 100–500 mcg
- Frequency
- 1× daily
- Notes
- SubQ/IM; typically run in 5–10 day cycles.
Reported research/reference doses for educational purposes only. Always verify against primary literature and applicable regulations. Not medical advice.
How it works
Semax modulates the brain's dopamine, serotonin, and noradrenaline systems and influences BDNF (brain-derived neurotrophic factor) expression. This supports synaptic plasticity, neuroprotection, and enhanced cognitive performance under stress or injury.
Common research uses
- Memory and learning enhancement
- Attention and focus research
- Neuroprotection studies
- Recovery after cognitive stress
Considerations
Research compound. Most robust data come from Russian studies. Generally well tolerated but should be used with caution and medical guidance.