SS-31
A mitochondrial-targeted peptide studied for cellular energy.
Overview
SS-31 (elamipretide) is a small synthetic peptide that targets the inner mitochondrial membrane. It is researched for protecting mitochondrial function in conditions from heart failure to kidney disease, and has become popular in longevity protocols for its role in cellular energy production.
Dosing
Injection
- Starting dose
- 5 mg
- Common dose
- 10–40 mg
- Frequency
- 1× daily
- Notes
- Clinical trials used up to 40 mg/day subQ.
Reported research/reference doses for educational purposes only. Always verify against primary literature and applicable regulations. Not medical advice.
How it works
SS-31 binds cardiolipin, a lipid that supports the architecture of the inner mitochondrial membrane and the electron transport chain. By stabilizing cardiolipin, it improves ATP production and reduces reactive oxygen species, supporting cellular energy and resilience.
Common research uses
- Mitochondrial function research
- Cellular energy and ATP support
- Cardiac and renal protection studies
- Longevity and age-related decline protocols
Considerations
Research compound. Injectable use requires care with reconstitution. Evidence for clinical use is still developing. Research use only.